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edc-randomization-0.3.9


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توضیحات

Randomization classes for clinicedc/edc
ویژگی مقدار
سیستم عامل -
نام فایل edc-randomization-0.3.9
نام edc-randomization
نسخه کتابخانه 0.3.9
نگهدارنده []
ایمیل نگهدارنده []
نویسنده Erik van Widenfelt
ایمیل نویسنده ew2789@gmail.com
آدرس صفحه اصلی https://github.com/clinicedc/edc-randomization
آدرس اینترنتی https://pypi.org/project/edc-randomization/
مجوز GPL license, see LICENSE
|pypi| |actions| |codecov| |downloads| edc-randomization ================= Randomization objects for clinicedc projects Overview ++++++++ The ``Randomizer`` class emulates the randomization of a clincial trial participant in realtime. This module doesn't actually `randomize` in realtime. Instead, a CSV file is prepared in advance by the statistician. This CSV file lists the order in which subjects are to be randomized. The ``Randomizer`` class initially imports the entire list in order into a ``model``. When a subject is to be randomized, the ``Randomizer`` class selects the next available row from the model. A very basic ``randomization_list.csv`` prepared in advance might look like this:: site_name,sid,assignment temeke,1000,active temeke,1001,active temeke,1002,placebo temeke,1003,active temeke,1004,placebo temeke,1005,placebo ... For large multisite trials this may be thousands of lines ordered using some type of block randomization. This module will import (only once) all rows from the CSV file into a model. The ``Randomizer`` class selects and allocates in order by site_name one row per participant from the model. .. code-block:: python randomizer_cls = site_randomizers.get("default") randomizer_cls.randomize(subject_identifier=subject_identifier, ...) # or just: site_randomizers.randomize("default", subject_identifier=subject_identifier, ...) Usually, the ``Randomizer`` class is instantiated in a ``signal`` once the subject's eligibility is confirmed and the subject's informed consent is submitted. A `signal` attached to the subject's informed consent is a good place to do this assuming the sequence of events are 1) pass eligibility criteria, 2) complete informed consent, 3) `randomize` and issue study identifier 4) start baseline visit. .. code-block:: python @receiver( post_save, weak=False, sender=SubjectConsent, dispatch_uid="subject_consent_on_post_save", ) def subject_consent_on_post_save(sender, instance, raw, created, **kwargs): if not raw: if created: ... # randomize site_randomizers.randomize( "default", subject_identifier=instance.subject_identifier, report_datetime=instance.consent_datetime, site=instance.site, user=instance.user_created, ) ... Registering a randomizer ++++++++++++++++++++++++ The default ``Randomizer`` class is ``edc_randomization.randomizer.Randomizer``. Unless you indicate otherwise, it will be automatically registered with the site controller, ``site_randomizers`` with the name ``default``. It is recommended you access the ``Randomizer`` class through ``site_randomizers`` instead of directly importing. .. code-block:: python randomizer_cls = site_randomizers.get("default") Customizing the default randomizer ++++++++++++++++++++++++++++++++++ Some attributes of the default ``Randomizer`` class can be customized using ``settings`` attributes: .. code-block:: python EDC_RANDOMIZATION_LIST_PATH = 'path/to/csv_file' EDC_RANDOMIZATION_ASSIGNMENT_MAP = { "intervention": 1, "control": 2, } EDC_RANDOMIZATION_ASSIGNMENT_DESCRIPTION_MAP = { "intervention": "Fluconazole plus flucytosine", "control": "Fluconazole" } Creating a custom randomizer ++++++++++++++++++++++++++++ If you need to customize further, create a custom ``Randomizer`` class. In the example below, ``gender`` is added for a trial stratified by ``gender``. Custom ``Randomizer`` classes live in ``randomizers.py`` in the root of your app. The ``site_randomizers`` controller will ``autodiscover`` them. .. code-block:: python # my_app/randomizers.py @register() class MyRandomizer(Randomizer): name = "my_randomizer" model = "edc_randomization.myrandomizationlist" randomization_list_path = tmpdir assignment_map = {"Intervention": 1, "Control": 0} assignment_description_map = {"Intervention": "Fluconazole plus flucytosine", "Control": "Fluconazole"} extra_csv_fieldnames = ["gender"] def __init__(self, gender=None, **kwargs): self.gender = gender super().__init__(**kwargs) @property def extra_required_instance_attrs(self): return dict(gender=self.gender) @property def extra_model_obj_options(self): return dict(gender=self.gender) @classmethod def get_extra_list_display(cls): return [(4, "gender")] The ``register()`` decorator registers the custom class with ``site_randomizers``. With a custom randomizer, the default ``Randomizer`` class is no longer needed, update settings to prevent the default class from registering. Use the settings attribute: .. code-block:: python EDC_RANDOMIZATION_REGISTER_DEFAULT_RANDOMIZER = False Confirm this by checking the ``site_randomizers``: .. code-block:: python >>> randomizer_cls = site_randomizers.get("default") NotRegistered: A Randomizer class by this name ... >>> randomizer_cls = site_randomizers.get("my_randomizer") >>> randomizer_cls.name "my_randomizer" Manually Importing from CSV +++++++++++++++++++++++++++ A ``Randomizer`` class will call ``import_list`` when it is instantiated for the first time. If you want to load the CSV file manually, import the ``Randomizer`` class and call ``import_list()``. .. code-block:: python >>> randomizer_cls = site_randomizers.get("my_randomizer") >>> randomizer_cls.import_list() Import CSV data Randomizer: - Name: my_randomizer - Assignments: {'active': 1, 'placebo': 2} - Model: edc_randomization.myrandomizationlist - Path: /home/me/.etc/randomization_list.csv - Imported 5 SIDs for randomizer `my_randomizer` into model `edc_randomization.myrandomizationlist` from /home/me/.etc/randomization_list.csv. - Verified OK. Manually Export to CSV ++++++++++++++++++++++ .. code-block:: python >>> from edc_randomization.utils import export_randomization_list >>> export_randomization_list(randomizer_name="default",path="~/", username="erikvw") If the user does not have permissions to view the randomizationlist table, a ``RandomizationListExporterError`` will be raised: .. code-block:: python RandomizationListExporterError: User `erikvw` does not have permission to view 'edc_randomization.randomizationlist' .. |pypi| image:: https://img.shields.io/pypi/v/edc-randomization.svg :target: https://pypi.python.org/pypi/edc-randomization .. |actions| image:: https://github.com/clinicedc/edc-randomization/workflows/build/badge.svg?branch=develop :target: https://github.com/clinicedc/edc-randomization/actions?query=workflow:build .. |codecov| image:: https://codecov.io/gh/clinicedc/edc-randomization/branch/develop/graph/badge.svg :target: https://codecov.io/gh/clinicedc/edc-randomization .. |downloads| image:: https://pepy.tech/badge/edc-randomization :target: https://pepy.tech/project/edc-randomization


زبان مورد نیاز

مقدار نام
>=3.8 Python


نحوه نصب


نصب پکیج whl edc-randomization-0.3.9:

    pip install edc-randomization-0.3.9.whl


نصب پکیج tar.gz edc-randomization-0.3.9:

    pip install edc-randomization-0.3.9.tar.gz