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caspo-4.0.1


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توضیحات

Reasoning on the response of logical signaling networks with Answer Set Programming
ویژگی مقدار
سیستم عامل -
نام فایل caspo-4.0.1
نام caspo
نسخه کتابخانه 4.0.1
نگهدارنده []
ایمیل نگهدارنده []
نویسنده Santiago Videla
ایمیل نویسنده santiago.videla@gmail.com
آدرس صفحه اصلی http://bioasp.github.io/caspo/
آدرس اینترنتی https://pypi.org/project/caspo/
مجوز GPLv3+
[![Conda package](https://anaconda.org/bioasp/caspo/badges/version.svg)](https://anaconda.org/bioasp/caspo) [![Documentation Status](https://readthedocs.org/projects/caspo/badge/?version=latest)](http://caspo.readthedocs.io/en/latest/?badge=latest) [![license](https://img.shields.io/badge/license-GPLv3+-brightgreen.svg)](https://www.gnu.org/licenses/gpl.html) [![Gitter](https://badges.gitter.im/bioasp/community.svg)](https://gitter.im/bioasp/community?utm_source=badge&utm_medium=badge&utm_campaign=pr-badge) ### Reasoning on the response of logical signaling networks The manual identification of logic rules underlying a biological system is often hard, error-prone and time consuming. Further, it has been shown that, if the inherent experimental noise is considered, many different logical networks can be compatible with a set of experimental observations. Thus, automated **inference of logical networks from experimental data** would allow for identifying admissible large-scale logic models saving a lot of efforts and without any a priori bias. Next, once a family a logical networks has been identified, one can suggest or **design new experiments** in order to reduce the uncertainty provided by this family. Finally, one can **look for intervention strategies** that force a set of target species or compounds into a desired steady state. Altogether, this constitutes a pipeline for automated reasoning on logical signaling networks. Hence, the aim of **caspo** is to implement such a pipeline providing a powerful and easy-to-use software tool for systems biologists. ### Documentation Detailed documentation about how to install and use **caspo** is available at http://caspo.readthedocs.io. ### Samples Sample files are included with **caspo** and available for [download](http://bioasp.github.io/caspo/data.zip) ### Citation caspo: a toolbox for automated reasoning on the response of logical signaling networks families. (2017). Bioinformatics. [DOI](https://doi.org/10.1093/bioinformatics/btw738) ### Related publications * Designing experiments to discriminate families of logic models. (2015). Frontiers in Bioengineering and Biotechnology 3:131. [DOI](http://dx.doi.org/10.3389/fbioe.2015.00131) * Learning Boolean logic models of signaling networks with ASP. (2015). Theoretical Computer Science. [DOI](http://dx.doi.org/10.1016/j.tcs.2014.06.022) * Reasoning on the Response of Logical Signaling Networks with ASP. (2014). John Wiley & Sons, Inc. [DOI](http://dx.doi.org/10.1002/9781119005223.ch2) * Minimal intervention strategies in logical signaling networks with ASP. (2013). Theory and Practice of Logic Programming. [DOI](http://dx.doi.org/10.1017/S1471068413000422) * Exhaustively characterizing feasible logic models of a signaling network using Answer Set Programming. (2013). Bioinformatics. [DOI](http://dx.doi.org/10.1093/bioinformatics/btt393) * Revisiting the Training of Logic Models of Protein Signaling Networks with a Formal Approach based on Answer Set Programming. (2012) The 10th Conference on Computational Methods in Systems Biology. [DOI](http://dx.doi.org/10.1007/978-3-642-33636-2_20)


نحوه نصب


نصب پکیج whl caspo-4.0.1:

    pip install caspo-4.0.1.whl


نصب پکیج tar.gz caspo-4.0.1:

    pip install caspo-4.0.1.tar.gz