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Viola-SV-1.0.2


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توضیحات

SV signature analysis tool with custom SV type
ویژگی مقدار
سیستم عامل OS Independent
نام فایل Viola-SV-1.0.2
نام Viola-SV
نسخه کتابخانه 1.0.2
نگهدارنده []
ایمیل نگهدارنده []
نویسنده Itsuki Sugita, Shohei Matsuyama, Hiroki Dobashi
ایمیل نویسنده itsukiisogin@gmail.com
آدرس صفحه اصلی https://github.com/dermasugita/Viola-SV
آدرس اینترنتی https://pypi.org/project/Viola-SV/
مجوز Apache License 2.0
************************ Welcom to Viola Package! ************************ .. _here: https://viola-sv.readthedocs.io .. image:: https://viola-sv.readthedocs.io/en/latest/_static/Viola-logo/JPG/wide.jpg |PyPI|_ |PyVersion|_ |License|_ |DOI|_ |DOC|_ |COV|_ |Issue|_ |Downloads|_ .. |PyPI| image:: https://img.shields.io/pypi/v/viola-sv .. _PyPI: https://pypi.org/project/Viola-SV/ .. |PyVersion| image:: https://img.shields.io/pypi/pyversions/viola-sv .. _PyVersion: https://pypi.org/project/Viola-SV/ .. |License| image:: https://img.shields.io/pypi/l/viola-sv .. _License: https://pypi.org/project/Viola-SV/ .. |DOI| image:: https://img.shields.io/badge/DOI-10.1093%2Fbioinformatics%2Fbtab662-9cf .. _DOI: https://academic.oup.com/bioinformatics/article/38/2/540/6371863 .. |DOC| image:: https://readthedocs.org/projects/viola-sv/badge/?version=latest .. _DOC: https://viola-sv.readthedocs.io .. |COV| image:: https://codecov.io/gh/dermasugita/Viola-SV/branch/master/graph/badge.svg?token=G7TI1S6FY2 .. _COV: https://codecov.io/gh/dermasugita/Viola-SV .. |Issue| image:: https://img.shields.io/badge/issue%20tracking-github-brightgreen .. _Issue: https://github.com/dermasugita/Viola-SV/issues .. |Downloads| image:: https://pepy.tech/badge/viola-sv/month .. _Downloads: https://pepy.tech/project/viola-sv Overview ============== Viola is a flexible and powerful python package designed specifically for analysis of genomic structural variant (SV) signatures. We provide following tools for SV signature analysis: * Custom SV classification tool * Feature matrix generator * SV signature extractor (NMF) with stability evaluation system. In addition to these, Viola offers a number of other useful utilities, including: * VCF filter that accepts genomic coordinates and INFO/FORMAT columns. * VCF merging tool with user-defined thresholds. * Breakends-to-breakpoint converter with SVTYPE inference. * Microhomology inference. * VCF-to-BEDPE conversion. * Command line tools for light users. Currently, Viola supports four popular SV callers as input VCF files: * Manta * Delly * Lumpy * Gridss In the future, we plan to support more SV callers! Installation ========================= The package can be installed with ``pip``: .. code:: console $ pip install viola-sv To import Viola in your script, simply run below: .. code:: python import viola Command line tools: .. code:: console $ viola <command> [something] Prerequisites ============== Python version 3.6 or newer. Recommended Environment ======================= * OS * Linux * Mac * Script Manager * Jupyter Notebook/Jupyter Lab * Google Colaboratory Docker support is coming soon! How to Learn Viola =================== As a first step we recommend the `Quick Start`_ page where you can see the basic behaviour of Viola. A good second step is to read the `Signature Analysis Tutorial`_ page. For command line interfaces, see `CLI tutorial`_. If you want to get a deeper understanding of how Viola objects are structured, how filtering works and how merging works, please refer to the `User Guide`_. Manuals for individual classes/methods/functions are available in the `API Reference`_. For further discussion, please join our `google group`_! We're waiting for your comments, ideas, and requests. The questions about how to use Viola-SV are also welcome! .. _google group: https://groups.google.com/g/viola-users Documentation ============= - `Documentation Home`_ - `Quick Start`_ - `Signature Analysis Tutorial`_ - `API Reference`_ .. _Documentation Home: https://viola-sv.readthedocs.io/ .. _Quick Start: https://viola-sv.readthedocs.io/en/1.0.x-stable-doc/quickstart.html .. _Signature Analysis Tutorial: https://viola-sv.readthedocs.io/en/1.0.x-stable-doc/signature_analysis.html .. _API Reference: https://viola-sv.readthedocs.io/en/1.0.x-stable-doc/reference/index.html .. _User Guide: https://viola-sv.readthedocs.io/en/1.0.x-stable-doc/userguide/index.html .. _CLI tutorial: https://viola-sv.readthedocs.io/en/1.0.x-stable-doc/userguide/cli.html Publications ============= Sugita, I., Matsuyama, S., Dobashi, H., Komura, D. & Ishikawa, S. Viola: a structural variant signature extractor with user-defined classifications. Bioinformatics (2021) doi:10.1093/bioinformatics/btab662.


نیازمندی

مقدار نام
>=1.1.5 pandas
>=0.6.8 PyVCF
>=3.1.0 intervaltree
>=1.79 biopython
>=0.24.2 scikit-learn
>=1.5.4 scipy
>=8.0.4 click
- pytest


زبان مورد نیاز

مقدار نام
>=3.6 Python


نحوه نصب


نصب پکیج whl Viola-SV-1.0.2:

    pip install Viola-SV-1.0.2.whl


نصب پکیج tar.gz Viola-SV-1.0.2:

    pip install Viola-SV-1.0.2.tar.gz