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PyCTD-0.5.9


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توضیحات

Importing and querying CTD
ویژگی مقدار
سیستم عامل OS Independent
نام فایل PyCTD-0.5.9
نام PyCTD
نسخه کتابخانه 0.5.9
نگهدارنده []
ایمیل نگهدارنده []
نویسنده Christian Ebeling
ایمیل نویسنده christian.ebeling@scai.fraunhofer.de
آدرس صفحه اصلی https://github.com/cebel/pyctd
آدرس اینترنتی https://pypi.org/project/PyCTD/
مجوز Apache 2.0 License
PyCTD |stable_build| ==================== |stable_documentation| |pypi_license| `PyCTD <http://pyctd.readthedocs.io>`_ is a Python package to access and query chemical–gene/protein interactions, chemical–disease and gene–disease relationships by data provided by the `Comparative Toxicogenomics Database <http://ctdbase.org>`_ . Data are installed in a (local or remte) RDBMS enabling bioinformatic algorithms very fast response times to sophisticated queries and high flexibility by using SQLAlchemy database layer. PyCTD is developed by the `Department of Bioinformatics <https://www.scai.fraunhofer.de/en/business-research-areas/bioinformatics.html>`_ at the Fraunhofer Institute for Algorithms and Scientific Computing `SCAI <https://www.scai.fraunhofer.de/en.html>`_ For more in for information about CTD go to `this section in the documentation <http://pyctd.readthedocs.io/en/latest/ctd.html>`_. |er_model| This development is supported by following `IMI <https://www.imi.europa.eu/>`_ projects: - `AETIONOMY <http://www.aetionomy.eu/>`_ and - `PHAGO <http://www.phago.eu/>`_. |imi_logo| |aetionomy_logo| |phago_logo| |scai_logo| Supported Databases ------------------- `PyCTD` uses `SQLAlchemy <http://sqlalchemy.readthedocs.io>`_ to cover a wide spectrum of RDMSs (Relational database management system). For best performance MySQL or MariaDB is recommended. But if you have no possibility to install software on your system SQLite - which needs no further installation - also works. Following RDMSs are supported (by SQLAlchemy): 1. Firebird 2. Microsoft SQL Server 3. MySQL / `MariaDB <https://mariadb.org/>`_ 4. Oracle 5. PostgreSQL 6. SQLite 7. Sybase Getting Started --------------- This is a quick start tutorial for impatient. Installation |pypi_version| |python_versions| ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ PyCTD can be installed with `pip <https://pip.pypa.io/en/stable/>`_. .. code-block:: bash pip install pyctd If you fail because you have no rights to install use superuser (sudo on Linux before the commend) or ... .. code-block:: bash pip install --user pyctd If you want to make sure you are installing this under python3 use ... .. code-block:: bash python3 -m pip install pyctd SQLite ~~~~~~ .. note:: If you want to use SQLite as your database system, because you ... - have no possibility to use RDMSs like MySQL/MariaDB - just test pyctd, but don't want to spend time in setting up a database skip the next *MySQL/MariaDB setup* section. But in general we recommend MySQL or MariaDB as your RDBMS. If you don't know what all that means skip the section *MySQL/MariaDB setup*. Don't worry! You can always later change the configuration. For more information about changing database system later go to the subtitle *Changing database configuration* `Changing database configuration <http://pyctd.readthedocs.io/en/latest/installation.html>`_ in the documentation on readthedocs. MySQL/MariaDB Setup ~~~~~~~~~~~~~~~~~~~ Log in MySQL as root user and create a new database, create a user, assign the rights and flush privileges. .. code-block:: mysql CREATE DATABASE pyctd CHARACTER SET utf8 COLLATE utf8_general_ci; GRANT ALL PRIVILEGES ON pyctd.* TO 'pyctd_user'@'%' IDENTIFIED BY 'pyctd_passwd'; FLUSH PRIVILEGES; Start a python shell and set the MySQL configuration. If you have not changed anything in the SQL statements ... .. code-block:: python import pyctd pyctd.set_mysql_connection() If you have used you own settings, please adapt the following command to you requirements. .. code-block:: python import pyctd pyctd.set_mysql_connection(host='localhost', user='pyctd_user', passwd='pyctd_passwd', db='pyctd') Updating ~~~~~~~~ The updating process will download the files provided by the CTD team on the `download page <http://ctdbase.org/downloads/>`_ .. warning:: Please note that download files needs 1,5Gb of disk space and the update takes ~2h (depending on your system) .. code-block:: python import pyctd pyctd.update() Example Query ~~~~~~~~~~~~~ .. code-block:: python >>> query = pyctd.query() >>> results = query.get_chem_gene_interaction_actions(gene_name='APP', interaction_action='meman%', limit=1) >>> first_result = r >>> r.chemical Memantine >>> r.pubmed_ids [21290839] >>> r.chemical.drugbank_ids [DB014043] More Information ---------------- See the `installation documentation <http://pyctd.readthedocs.io/en/latest/installation.html>`_ for more advanced instructions. Also, check the change log at :code:`CHANGELOG.rst`. CTD Tools and License (use of data) ----------------------------------- CTD provides also many online `query interfaces <http://ctdbase.org/search/>`_ and `tools to analyse data <http://ctdbase.org/tools/>`_ on their website. Please be aware of the `CTD license <http://ctdbase.org/about/legal.jsp>`_ which allows the use of data only for research and educational purposes. Medical treatment decisions should not be made based on the information in CTD. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the MDI Biological Laboratory and NC State University. Links ----- Comparative Toxicogenomics Database (CTD) - `CTD website <http://ctdbase.org/>`_ - `All CTD publications <http://ctdbase.org/about/publications/>`_ - `CTD download page <http://ctdbase.org/downloads/>`_ PyCTD - Documented on `Read the Docs <http://pyctd.readthedocs.io/>`_ - Versioned on `GitHub <https://github.com/cebel/pyctd>`_ - Tested on `Travis CI <https://travis-ci.org/cebel/pyctd>`_ - Distributed by `PyPI <https://pypi.python.org/pypi/pyctd>`_ - Chat on `Gitter <https://gitter.im/pyctd/Lobby>`_ .. |stable_build| image:: https://travis-ci.org/cebel/pyctd.svg?branch=master :target: https://travis-ci.org/cebel/pyctd :alt: Stable Build Status .. |stable_documentation| image:: https://readthedocs.org/projects/pyctd/badge/?version=latest :target: http://pyctd.readthedocs.io/en/latest/ :alt: Development Documentation Status .. |pypi_license| image:: https://img.shields.io/pypi/l/PyCTD.svg :alt: Apache 2.0 License .. |python_versions| image:: https://img.shields.io/pypi/pyversions/PyCTD.svg :alt: Stable Supported Python Versions .. |pypi_version| image:: https://img.shields.io/pypi/v/PyCTD.svg :alt: Current version on PyPI .. |phago_logo| image:: https://owncloud.scai.fraunhofer.de/index.php/apps/files_sharing/ajax/publicpreview.php?x=1920&y=562&a=true&file=phago-logo.jpg&t=7llp11KwSiuXYOh&scalingup=0 :target: https://www.imi.europa.eu/content/phago :alt: PHAGO project logo .. |aetionomy_logo| image:: https://owncloud.scai.fraunhofer.de/index.php/apps/files_sharing/ajax/publicpreview.php?x=1920&y=562&a=true&file=aetionomy-logo.png&t=5ClUGTZRAYkeb7m&scalingup=0 :target: http://www.aetionomy.eu/en/vision.html :alt: AETIONOMY project logo .. |imi_logo| image:: https://owncloud.scai.fraunhofer.de/index.php/apps/files_sharing/ajax/publicpreview.php?x=1920&y=562&a=true&file=imi-logo.png&t=Uvw79bTxGyd07oo&scalingup=0 :target: https://www.imi.europa.eu/ :alt: IMI project logo .. |scai_logo| image:: https://owncloud.scai.fraunhofer.de/index.php/apps/files_sharing/ajax/publicpreview.php?x=1920&y=562&a=true&file=scai-logo.png&t=fyJo2GzFDLNypho&scalingup=0 :target: https://www.scai.fraunhofer.de/en/business-research-areas/bioinformatics.html :alt: SCAI project logo .. |er_model| image:: https://owncloud.scai.fraunhofer.de/index.php/apps/files_sharing/ajax/publicpreview.php?x=1920&y=562&a=true&file=pyctd_er_model.png&t=QUm8KPPnNGoH8wp&scalingup=0 :target: http://pyctd.readthedocs.io/en/latest/ :alt: Entity relationship model


نحوه نصب


نصب پکیج whl PyCTD-0.5.9:

    pip install PyCTD-0.5.9.whl


نصب پکیج tar.gz PyCTD-0.5.9:

    pip install PyCTD-0.5.9.tar.gz